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⚠️ Educational only · Not medical advice · Consult a doctor · Most peptides are research-only / not FDA-approved for human use
⚠️ Educational only · Not medical advice · Consult a doctor · Most peptides are research-only / not FDA-approved for human use
Also: CJC-1295 DAC, Mod GRF 1-29
GHRH AnalogLast Updated: April 1, 2026
CJC-1295 (also known as CJC-1295 DAC, Mod GRF 1-29) is a prominently researched experimental compound classified strictly within the GHRH Analog framework. Operating primarily through advanced pharmacological pathways, it functions by stimulates prolonged GH and IGF-1 release by mimicking the body's natural GHRH signal to the pituitary gland. Preserves natural pulsatile GH release pattern. with a documented biological half-life of roughly 168 hours, in preclinical investigative trials and independent academic studies, researchers utilizing CJC-1295 have documented significant, quantifiable biological outcomes, primarily focusing on muscle growth, fat loss, recovery. Typical research protocols investigate administering 1000 to 1000mcg via subq pathways 3x/week. However, it is critically important to understand that while CJC-1295 demonstrates profound physiological potential in highly controlled laboratory settings, it remains classified strictly as a research chemical and has not been approved by the United States Food and Drug Administration (FDA) for human therapeutic, diagnostic, or dietary consumption. Independent chemical analysis via rigorous third-party Certificate of Analysis (COA) testing utilizing High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) remains the industry gold standard for verifying its base elemental stability when reconstituted appropriately in sterile bacteriostatic water.
Stimulates prolonged GH and IGF-1 release by mimicking the body's natural GHRH signal to the pituitary gland. Preserves natural pulsatile GH release pattern.
Teichman et al. (J. Clin. Endocrinol. Metab.): Single injection increases GH 2-10x for 6+ days and IGF-1 1.5-3x for 9-11 days in healthy adults. Well-tolerated at 30-60 µg/kg.
moderateIonescu & Bhatt (J. Clin. Endocrinol. Metab.): Demonstrates 7.5-fold increase in basal GH, 46% increase in mean GH, and 45% increase in IGF-1 while preserving natural pulsatile pattern.
moderateAnimal study shows CJC-1295 increases total pituitary RNA and GH mRNA, suggesting proliferation of somatotroph cells for sustained GH production.
preclinicalOften stacked with Ipamorelin; injection site reactions possible. Not FDA-approved.
⚠️ For educational purposes only. Not medical advice. Consult a healthcare professional before using any peptide.
CJC-1295 DAC version has 7-day half-life. Mod GRF 1-29 (no DAC) has ~30min half-life.
Last updated: 2026-01 · Laws change frequently. Verify current status in your jurisdiction.
Week 1
Improved sleep depth; occasional GH flush sensation; increased hunger in morning
Weeks 2-4
Elevated energy and faster post-workout recovery; mild water retention
Month 2-3
Measurable lean mass improvements; visible fat redistribution; IGF-1 elevation confirmed on bloodwork
Long-term
Sustained GH axis support; anti-aging body composition benefits; improved bone density over 6+ months
| Side Effect | Incidence | Severity |
|---|---|---|
Water retention Usually resolves after first 2-4 weeks | ~15% of users | mild |
Headache / GH flush | ~8% of users | mild |
Injection site reaction | ~5% of users | mild |
Temporary fatigue | ~5% of users | mild |
Incidence rates sourced from published clinical trial data where available; otherwise based on community research observations.
Finding verified, high-purity CJC-1295 requires rigorous COA verification. We independently evaluate vendors based on third-party HPLC testing, purity thresholds (≥98%), and batch-specific documentation.
View COA-Verified CJC-1295✓ Third-party tested·✓ US shipping·✓ COA on every batch
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