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CJC-1295 / Ipamorelin

"The GH Stack"

CJC-1295IpamorelinGrowth Hormone

Benefits

Optimized GH release, lean muscle growth, fat loss, improved sleep and recovery

Why This Blend?

CJC-1295 provides sustained GHRH signaling (extended GH elevation), while Ipamorelin triggers acute, clean GH pulses without raising cortisol or prolactin. Together, they amplify the GH response beyond what either achieves alone.

Mechanism of Action

CJC-1295 mimics GHRH to maintain elevated baseline GH via the GHRH receptor, with a 7-day half-life (DAC version). Ipamorelin mimics ghrelin at the GHS receptor for acute, selective GH release. Dual-receptor activation produces a synergistic GH pulse.

Dosing Protocol

Typical Ratio: CJC-1295 1000-2000mcg + Ipamorelin 200-300mcg per injection

Inject together SubQ, pre-bed or morning fasted. CJC-1295 DAC: 2x/week. Mod GRF 1-29 (no DAC): 1-3x daily with Ipamorelin. Cycle 8-16 weeks.

Expected Timeline

Week 1

Improved sleep depth; GH flush sensation; increased appetite

Weeks 2–4

Enhanced recovery and energy; early body composition changes

Months 2–3

Measurable lean mass gain; visible fat loss; elevated IGF-1 on bloodwork

Long-term

Sustained anti-aging benefits; improved body composition; better bone density

Supporting Studies

CJC-1295 sustained GH/IGF-1 elevation

Single injection increases GH 2-10x for 6+ days and IGF-1 1.5-3x.

moderate

Ipamorelin selective GH release

Releases GH potently and selectively without raising cortisol or prolactin.

moderate

Safety Notes

One of the safest GH peptide combinations. No significant cortisol or prolactin elevation. Not FDA-approved.

📚 Individual Peptide Profiles

CJC-1295 →Ipamorelin →