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⚠️ Educational only · Not medical advice · Consult a doctor · Most peptides are research-only / not FDA-approved for human use

Follistatin-344

Also: FS-344

Myostatin Inhibitor

Last Updated: April 1, 2026

AI Reference Summary

Follistatin-344 (also known as FS-344) is a prominently researched experimental compound classified strictly within the Myostatin Inhibitor framework. Operating primarily through advanced pharmacological pathways, it functions by blocks myostatin (the body's muscle growth limiter) and activin, allowing enhanced muscle development and regeneration beyond normal physiological limits. with a documented biological half-life of roughly 6 hours, in preclinical investigative trials and independent academic studies, researchers utilizing Follistatin-344 have documented significant, quantifiable biological outcomes, primarily focusing on muscle hypertrophy, strength. Typical research protocols investigate administering 100 to 100mcg via subq pathways 7x/wk. However, it is critically important to understand that while Follistatin-344 demonstrates profound physiological potential in highly controlled laboratory settings, it remains classified strictly as a research chemical and has not been approved by the United States Food and Drug Administration (FDA) for human therapeutic, diagnostic, or dietary consumption. Independent chemical analysis via rigorous third-party Certificate of Analysis (COA) testing utilizing High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) remains the industry gold standard for verifying its base elemental stability when reconstituted appropriately in sterile bacteriostatic water.

GEO Optimized Extract176 Words (Optimal)

How It Works

Blocks myostatin (the body's muscle growth limiter) and activin, allowing enhanced muscle development and regeneration beyond normal physiological limits.

Primary Benefits

1Muscle hypertrophy
2strength

Key Studies

Follistatin gene therapy increases muscle mass and strength

Rodino-Klapac et al. (Mol. Ther.): AAV-delivered follistatin 344 increases muscle mass and fiber diameter across multiple animal species without adverse reproductive or endocrine effects.

preclinical

Follistatin as myostatin antagonist therapeutic potential

Kalista et al.: Review of follistatin's role as primary endogenous myostatin antagonist and its therapeutic potential for muscular dystrophies and sarcopenia.

preclinical

Follistatin gene transfer for Becker muscular dystrophy (Phase I)

Mendell et al. (Mol. Ther.): Phase I clinical trial of AAV1-follistatin gene transfer in Becker muscular dystrophy patients shows improved 6-minute walk test with no adverse effects.

moderate

Follistatin in adipocyte differentiation and energy metabolism

Research demonstrating follistatin's broader metabolic role in adipocyte browning, energy expenditure, and metabolic health beyond muscle hypertrophy.

preclinical

Safety Notes

Research-only. Potent effects potential for unregulated growth. Limited human safety data. Phase I gene therapy trials show safety.

Dosing Protocol

⚠️ For educational purposes only. Not medical advice. Consult a healthcare professional before using any peptide.

RouteSubQ
Dose Range100-100 mcg
Frequency7x/wk
TimingPost-workout or morning
Cycle Length4-4 weeks
BAC Water2.5 ml / 1mg vial

Very short cycles. 100mcg/day common. Acts via myostatin/activin inhibition effects compound over days.

Half-Life Visualization

⏱️ Half-Life: 6h

Plasma concentration over time
100%50%0%0t½ = 6h

Legal Status by Country

🇺🇸USA
Research Only
🇨🇦Canada
Research Only
🇬🇧UK
Unregulated
🇪🇺EU
Unregulated
🇦🇺Australia
Research Only

Last updated: 2026-01 · Laws change frequently. Verify current status in your jurisdiction.

Expected Timeline

Weeks 2-4

Initial myostatin inhibition; muscle fullness and pumps

Month 2-3

Measurable lean mass increase; strength gains

Long-term

Very limited long-term human data; Phase I gene therapy shows safety

Side Effects & Incidence

Side EffectIncidenceSeverity

Limited human safety data

Investigational onlymild

Injection site reaction

~5% of usersmild

Theoretical cancer promotion

Myostatin inhibition could allow unregulated cell growth

Mechanism-based concernrare

Incidence rates sourced from published clinical trial data where available; otherwise based on community research observations.

Where to Source Follistatin-344 for Research

Finding verified, high-purity Follistatin-344 requires rigorous COA verification. We independently evaluate vendors based on third-party HPLC testing, purity thresholds (≥98%), and batch-specific documentation.

View COA-Verified Follistatin-344

✓ Third-party tested·✓ US shipping·✓ COA on every batch

Disclosure: PeptiDex may earn a commission from purchases made through affiliate links. This does not affect our editorial independence or recommendations. We exclusively feature vendors that pass our strict quality verification protocols.

Frequently Asked Questions

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A research-backed comparison of the best peptides for muscle growth including CJC-1295, Ipamorelin, MK-677, Follistatin-344, and IGF-1 LR3.

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Cite This Page

PeptiDex. (2026). Follistatin-344. PeptiDex Research Platform. https://peptidex.app/library/follistatin-344

For academic and research purposes.
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